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Merck Operations Manager in Durham, North Carolina

Job Description

Our Hilleman & Teknika Manufacturing Sites in Durham, NC are hiring across multiple products and processes. The hiring team will determine based on your experience and skill set where you would make the greatest positive impact as an Operations Manager.

The role of Operations Manager at our Company's Durham facility is a manufacturing first level management role. The Operations Manager will provide direction, coaching, and technical expertise to operations personnel who are responsible for the manufacturing processes. They will also actively manage their assigned team to reliably support customer demand. This may include hiring as needed, employee development, coaching, and performance management.

Additionally, this role provides the opportunity to become proficient in the use of manufacturing systems and build knowledge of site procedures in order to resolve process/equipment issues, minimize downtime, and ensure product quality.

The Operations Manager leads the manufacturing process with a team assigned to cell culture, fermentation, bacterial propagation, purification, filling, lyophilization, crimping/sealing, product inspection, media preparation and/or sterile assembly, as well as other production-related activities.

We are hiring for a variety of shifts/schedules. Typical shifts are either 10 hour shifts or 12 hour rotating shifts (day and night). Applicants will have the ability to share their preference for shift/schedule if selected for interview.


Employee Development / People Management

  • Develop, motivate, and manage a team to ensure reliable manufacturing process execution

  • Assign yearly performance objectives for the team in alignment with department and site goals

  • Provide regular feedback and coaching to employees on work performance

  • Provide leadership to the team as needed based on the team’s capabilities and maturity

  • Build team culture and mediate conflict as needed

Process Execution / Continuous Improvement

  • Provide a leadership presence on the manufacturing floor

  • Champion standard work to drive consistent use of best practices across teams

  • Assist the team in troubleshooting issues to minimize downtime and maintain product quality

  • Identify opportunities to improve the process (e.g. cycle times, ease of execution, reliability)

  • Support work as needed to implement improvements (e.g. scheduling, staffing, protocol execution)

  • Coach team members in executing smaller improvement projects in their operational area

  • Represent Operations on project teams as needed


  • Lead and support daily (Tier) meetings to facilitate flow of information up/down through the organization

  • Hold regular team meetings to cascade information and collect team feedback

  • Provide clear consistent communication from shift to shift

  • Escalate issues as needed to ensure the right support/awareness is given to issues as they arise

  • Serve as a Subject Matter Expert (SME) during tours to provide area/process overview information to visitors/auditors upon request

Quality & Safety Compliance

  • Foster strong safety culture on the team through actions, coaching, and prioritization

  • Coach individuals when reporting safety issues and completing corrective/preventative actions

  • Drive culture of compliance through actions, consistent quality-driven decision making, and coaching of the team (e.g. documentation, housekeeping, area 5S, etc.)

  • Participate in safety/regulatory audits (i.e. tours, topic discussion)


  • Coach the team to ensure SAP transaction completion is timely and accurate

  • Manage team staffing and overtime to support customer demand while meeting budget targets

  • Recognize opportunities for cost savings and communicates them for potential project chartering


  • High School Diploma AND at least Six (6) years of experience in a manufacturing, technical, support, or Military role OR

  • Bachelor’s degree in a technical field AND at least Four (4) years of experience in a manufacturing, technical, support, or Military role

  • Willingness to work a flexible schedule covering various shifts

  • Demonstrated ability to lead a team (i.e. experience leading directly as a supervisor/coach or indirectly as part of a project or through routine process execution)

  • Ability to manage multiple priorities and coordinate people/resources to meet a production schedule

  • Strong interpersonal, communication, and problem-solving skills


  • Previous supervisory experience

  • Experience in Good Manufacturing Practices (GMP)

  • Experience using electronic manufacturing systems (e.g. PAS-X, SAP, Delta-V, GLIMS etc.)

  • Experience interacting with regulatory auditors as part of area tours and/or topic discussion

  • Certified Yellow Belt/Green Belt/Black Belt

Our Manufacturing & Supply Division is committed to be the most trusted supplier of bio-pharmaceuticals worldwide. Our facilities, along with our external contractors, suppliers, and partners, create an interdependent global manufacturing network that’s committed to delivering a high quality, reliable supply to customers and patients on time, every time.

Merck & Co., Inc., Kenilworth, New Jersey, USA is known as “Merck” in the United States, Canada & Puerto Rico. We are known as “MSD” in Europe, Middle East, Africa, Latin America & Asia Pacific. We are a global biopharmaceutical leader with a diverse portfolio of prescription medicines, oncology, vaccines and animal health products.

We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to Inspire our employees as we learn, develop and grow in our careers. We are proud of our 125 years of service to humanity and continue to be one of the world’s biggest investors in Research & Development.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.





In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

If you need an accommodation for the application process please email us at [email protected]

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster at

EEOC GINA Supplement​ at

OFCCP EEO Supplement at

OFCCP Pay Transparency Rule at

We are an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Search Firm Representatives Please Read Carefully

Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:




VISA Sponsorship:


Travel Requirements:


Flexible Work Arrangements:

Not Specified


1st - Day, 2nd - Evening, 3rd - Night

Valid Driving License:


Hazardous Material(s):

Number of Openings:


Requisition ID: R52974