Thermo Fisher Scientific Scientist III, Protein Expression in Frederick, Maryland

Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

The individual will work as part of the Cell Biology R&D team to support ongoing projects and/or lead new projects within the Thermo Fisher product commercialization process under the Gibco™ brand.

The successful candidate will possess a strong background in mammalian cell culture for protein expression, with experience from microtiter plate scale to rocker or stirred tank bioreactor scale. Strong experience with operating, optimizing, troubleshooting multi-liter stirred tank bioreactors is essential. Experience in molecular biology for plasmid generation, amplification, and purification is desirable. The candidate will require strong organizational skills to support full documentation of new product development for complex projects. Ability to multitask and maintain a results-oriented focus is essential.

The candidate will be required to maintain accurate lab notebooks and training files in accordance with relevant Thermo Fisher required standards to support patent application and defense as well as other international standards (e.g., ISO compliance, GLP/GMP requirements, etc.).

Typical requirements will include preparing and presenting experimental data summaries and protocol writing. Perform literature searches related to products under development and new idea generation. Work with internal and external customers to troubleshoot problems and understand unmet needs. The successful candidate will make contributions to scientific literature and conferences and comply with all company safety regulations and procedures.


B.S or M.S. degree with a demonstrated background in protein expression and/or other closely related disciplines.


  • 3-5+ years industry or academic experience with mammalian (and/or insect) protein expression

  • Extensive experience operating rocker and stirred tank reactors at the multi-liter scale.

  • Experience in utilizing equipment for metabolite profiling, protein concentration determination, etc.

  • Standard molecular biology techniques including DNA cloning, plasmid preparation/purification

  • Protein expression/purification/characterization

  • PCR, gel electrophoresis; genomic sequencing and/or cell line engineering skills a plus

  • Demonstrated competence completing tasks under direct supervision

  • Solid technical writing skills

  • Excellent time management skills and multi-tasking capabilities

  • Excellent organizational skills

  • Strong verbal and written communication skills and the ability to interpret, summarize, and present scientific results in a clear, concise, accurate manner to both technical and non-technical audiences

  • Demonstrated ability to achieve results and solve problems.

This position does not offer relocation benefits.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.