Scientist, Analytical Development- Cell Therapy

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS’s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

Position Summary

The Potency Group within Cell Therapy Analytical Development is responsible for potency assay development and functional characterization for cell therapy products. The Scientist role will drive development of state-of-the art potency assays that support the company portfolio of preclinical and clinical-stage cell therapies. This role requires a strong understanding of T-cell activation and NK-cell biology, and expertise with the design and development of functional assays. The role calls for close collaboration with early discovery groups, process science groups, internal analytical functions, as well as with manufacturing sciences and technology, and quality organizations.

Key Responsibilities

• Directly accountable for potency assay development for early- and late-stage development programs, development of fit-for-purpose biological characterization assays, and assay training and transfer to internal and external QC labs.
• Develops or contributes to biological characterization strategies for cell therapeutics pre- and post-IND through licensure
• Develops or contributes to sound scientific strategy to support regulatory acceptance of biological assays in clinical development.
• Responsible for generation and documentation of results.
• Responsible for experimental design, execution, data review and analysis, document writing, and contribution to regulatory submissions.
• Collaborates with stakeholders in partner organizations on technical and strategic activities.

Qualifications & Experience

• PhD or MS in immunology, or related discipline (title commensurate with experience)
• Depth of understanding of molecular mechanisms of T and NK cell activation/suppression
• Technical experience with biological assay development across multiple molecular modalities
• Demonstrated experience with cell-based assays
• Experience in molecular/cell biology is advantageous
• Experience with single cell analysis is advantageous
• Knowledge of cGxP requirements preferred
• Strong history of rigorous science applied to drive technical accomplishments
• Strong organizational and project management skills
• Strong interpersonal and communication skills
• Track record of scientific accomplishments and publications

If you want to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients’ lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.

#LI-Onsite BMSCART

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

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