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Job Details

Merck & Co, Inc

Director, Center for Observational and Real-world Evidence (CORE) Oncology Pan Tumor ( MERCUSR135506ENUS)

Real Estate

District Director



Rahway, New Jersey, United States

Job Description

Subject to applicable law, all prospective hires will be required to demonstrate that they have been fully vaccinated for COVID-19 or intend to be vaccinated for COVID-19 by November 1, 2021, or qualify for a medical or religious accommodation to this vaccination requirement. Hired candidates who are not vaccinated by November 1, 2021, and who have not been approved for a legally-required medical or religious accommodation will be subject to disciplinary action up to and including termination of employment, subject to applicable law.

Our Oncology team is dedicated to delivering breakthrough innovations that extend and improve the lives of cancer patients worldwide. Our team of forward-thinking individuals achieve this through an unwavering commitment to support accessibility to medicine, providing new therapeutic solutions, and collaborating with governments and payers to ensure that people who need medicines have access to them. Our focus is on innovation and launch execution excellence; we translate breakthrough science into innovative medicines that help people with cancer across the globe.

Within the Center for Observational and Real World Evidence (CORE), the incumbent will lead efforts related to building capabilities enabling Oncology Real World Evidence (RWE) generation. This individual will be responsible for the development of oncology RWE data strategy and analytics to support our oncology products.

The individual in this role serves as a subject matter expert, who draws from expertise in oncology product development, real world data, RWE in oncology and data & analytics, and applies these skills to address asset level business and scientific questions. The incumbent will also be expected to stay abreast of advances and developments externally in the field of real world data and evidence generation, including engagements with data providers. The incumbent would harness quantitative skills, experience with large datasets, real world studies, and understanding of technical infrastructure in building real world data assets.

The incumbent will align the oncology RWE capabilities with the broader CORE RWE capabilities in partnership with the RDAI team. The incumbent will work closely with the product Value Evidence Sub team (VEST) leads to identify use cases where the capabilities can be applied. The incumbent will work closely with colleagues internally across functional areas who are also involved in data strategy and analytics to achieve efficiencies and shared goals as appropriate.

Primary responsibilities:

  • Establish a knowledge center within our company's related to data, methods and analytics for Oncology RWE and communicate on the RWE related initiatives and findings.

  • Provide expertise on real world data sources and their quality to inform partnership and collaboration opportunities that will maximize the use of oncology real world data within our company.

  • Develop and maintain pan tumor RWE strategy for CORE-Oncology, in collaboration with tumor VEST leads and cross functional partners.

  • Identify and evaluate data sources that will enable RWE generation; and establish collaborative agreements based on the company's data strategy and data vendor offerings.

  • Represent CORE and lead interactions with emerging real world data providers, understanding their products, and evaluate them on their quality and fitness of use for our company's research needs.

  • Provide leadership and oversight of standardization of delivery of research grade, real-time, patient-level data into our company.

  • Play a leading role and serve as a subject matter expert on scientific methods utilized in oncology RWE generation.

  • Create global standards for real world evidence in oncology (such as standard business rules, methods for common endpoints).

  • Develop, publish, and update standard business rules over time and provide requirements for their use within our company.

  • Collaborate with stakeholders within VESTs, data science teams, medical affairs, policy, commercial to understand oncology real world data, analytics, and evidence generation needs.

  • Lead RWE generation for pan tumor use cases and serve as the lead for matching the evidence needs for individual tumor teams to the appropriate data asset and provide methods expertise as needed.

  • Monitor and evaluate trends on use cases, methodological developments, established frameworks, treatment guidelines, and impact generated from Real World Evidence.

  • Effectively communicate the Oncology RWE strategy and outcomes from studies both internally and externally including dissemination of scientific material at congresses and through publications.

  • Engage with the experts worldwide in use of RWD and analytics and its application in oncology.

Education Minimum Requirement:

  • Doctoral or Masters’ degree from a recognized school of medicine, public health, management, pharmacy, economics or other related field

Required Experience and Skills:

  • Experience in Data Science, expertise/experience in the design and implementation of real-world evidence

  • A track record of scientific presentations and publications.

  • 3+ years relevant experience if Doctoral degree

  • 5+ years relevant experience, if Masters’ degree

Preferred Experience and Skills:

  • Doctoral degree

  • Experience in Oncology-related datasets, real world evidence generation methods expertise

  • Experience in Oncology-related outcomes research/epidemiology

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:



No relocation

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Flexible Work Arrangements:

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Requisition ID:R135506