Scientist, Leads Discovery and Optimization (Immunological Assays and HTS), (R1558713-en-us)
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Scientist – Leads Discovery and Optimization (Immunological Assays and HTS), Lawrenceville, NJ
The Leads Discovery & Optimization Group leverages technology, innovation, and broad scientific knowledge to deliver comprehensive in vitro data packages to support all phases of early drug discovery at BMS. We are seeking a highly motivated and innovative scientist to drive the development and implementation of biochemical and cell-based assays supporting Cardiovascular, Fibrosis and Immunology therapeutic areas. This candidate will be expected to have a breadth of cell-based assay and in vitro pharmacology expertise to support drug discovery projects from hit identification through lead optimization. Applicants must have a deep scientific and technical understanding of high-throughput screening techniques to develop complex cell-based, automated screening assays, especially in immune cell types, for application across drug discovery programs. Expertise in assay automation, high content imaging and flow cytometry platforms is preferred. The candidate will be responsible for technology innovation for high-throughput disease screening platforms. The candidate should possess strong collaborative and written/verbal communication skills and a positive attitude to interact with multiple stakeholders. He/she should demonstrate personal leadership within the group, scientific leadership both at the bench and at data analysis and be adept at multi-tasking. This position will spend substantial time at the lab bench for assay design and screening.
Position Overview/Key Responsibilities
- Ph.D. in Pharmacology or Immunology with a minimum of 2 years post-doctoral experience OR MS in related area and minimum of 10 years applied assay design and high-throughput screening experience in the pharmaceutical industry is required.
- Extensive knowledge of immunology, cell biology, and pharmacology are required in addition to understanding physiologically relevant cellular models.
- A wide breadth of superior assay design and screening skills in both biochemical and immune cell-based assay formats as well as experience in the application of modern technology and automation is required.
- Expertise in assay automation; plate-based high content imaging or flow cytometry assays is preferred.
- Demonstrated proficiency in big data analysis is required.
- A “cutting edge” awareness of new technology advances and scientific knowledge in the high- throughput screening field to apply for drug discovery program support is essential.
- Ability to create and maintain an effective scientific network through teamwork, excellent problem-solving skills and open collaborative style are of critical importance to the success of this role.
- Ability to communicate scientific methods and results clearly. Will be responsible for scientific presentations and reports for internal review meetings and scientific journals.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
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