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Translational Research - Proteomic Mass Spectrometry Expertise

Science and Research

Biological Research

Yearly

No

Cambridge, Massachusetts, United States

6000! This is the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients.<br><br>We seek a creative and collaborative scientist to join the Translational Research and Data Science group in Disease Area X and contribute to advancing novel therapeutics by enabling the discovery and validation of novel targets and biomarkers. In this role, you will focus on discovery and targeted proteomics of clinical samples from well-designed disease cohorts, applying competitive edge proteogenomic, mass spectrometry and aptamer/antibody-based approaches. <br><br>Your responsibilities will include:<br><br>- Developing and employing novel approaches to identify, profile and quantify biomarkers in clinical samples to support translational research across multiple therapeutic areas of unmet medical need, including hepatology, nephrology and respiratory with particular interest in fibrosis<br><br>- Establishing quantitative mass spectrometry and antibody/aptamer assays for measuring proteins in complex biological matrices (plasma, serum, urine, CSF), including data processing and analyses in support of translation to clinical validation /qualification<br><br>- Playing a key role in an interdisciplinary team of translational research/medical scientists, biologist and computational scientists<br><br>- Participating in alliances with external partners at top healthcare institutions, with the opportunity to publish your work<br><br>[#video#https://www.youtube-nocookie.com/embed/ggbnzRY9z8w{#400,300#}#/video#]