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Job Details

Bristol Myers Squibb

Director, Translational Research Oncology

Science and Research

Clinical Research Director


San Francisco, California, United States

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

The Oncogenesis Thematic Research Center at BMS is one of the fundamental research and early development engines delivering oncology therapeutics to patients. The Oncogenesis TRC has a major focus of exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable. The group integrates discovery research through translational and early clinical development and exploits state-of-the-art in vitro, in vivo and ex-vivo models of cancer biology to identify and validate targets and partners closely with colleagues in Translational Development, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.

Position Responsibilities

In the role as a Director within the Oncogenesis Translational Team, the ideal candidate:

  • Has real-world experience with the translational aspects of clinical trials, and a track record of designing, executing, and interpreting translational data to provide insight and support program decisions

  • Can serve as subject matter expert for health authority interactions

  • Provides scientific leadership and management on cross-site and cross-functional teams

  • Leads group of translational scientists whose activities span cell-based, in vivo, and clinical trial assays, samples, and data

  • Manage (directly and via direct and indirect reports) the selection, validation, and deployment of novel clinical-stage assay methods and analysis of data to accelerate development and provide insight into disease biology and drug mechanisms

  • Design and interpret experiments to define dose-schedules, patient selection markers and other biomarker readouts, combination strategies and pathways of drug resistance for oncology programs

  • Design and oversee execution of experiments to test hypotheses from clinical observations in preclinical model systems

  • Present key data at governance committees, internal forums, and external meetings

  • Author and oversee writing of study reports, patents, and peer-reviewed publications. Presentation of methods, results and conclusions to publishable standards

  • Lead the identification, planning and execution of collaborative projects with leading academic and commercial research groups worldwide.

  • Management and hiring responsibility for translational scientists including direct and indirect reports up to the Sr. Principal Scientist/ Associate Director level.

  • Supervise contract research organizations to achieve high standards of productivity and quality.

  • Manage projects to successful outcomes through scientific leadership, teamwork and influence, and direct reporting relationships

  • Mentor research staff through instruction, coaching, and guidance

  • Work across geographies and scientific domains


Basic Qualifications:

  • Bachelor’s Degree

    • 15+ years of academic and / or industry experience


  • Master’s Degree

    • 12+ years of academic and / or industry experience


  • Ph.D. or equivalent advanced degree in the Life Sciences

    • 8+ years of academic and / or industry experience

  • 6+ years of leadership experience

Preferred Qualifications:

  • Ph.D., or scientific experience and development equivalent to a Ph.D., with 12+ years of post-Ph.D. experience including 6+ years of drug discovery and development experience in an industry setting

  • Recognized expert in clinical translational studies including sampling, analysis, and interpretation of multiple data types

  • Strategic leader able to define program priorities, resources, and strategies

  • Experienced and successful manager able to build and motivate teams, define goals and objectives, provide guidance and mentorship, negotiate conflicts, and optimize deployment of team resources to achieve objectives

  • Comprehensive knowledge of cancer biology and drug development

  • Proven ability to derive novel insights from complex data

  • Ability to interpret and summarize scientific data in an accurate, critical and concise manner

  • Strong understanding, derived from direct participation, of the design and execution of clinical trials incorporating translational science and correlative endpoints

  • Expertise in biomarker discovery and development, with advanced skills in assay design, development, validation, and troubleshooting

  • Experienced in the integration of preclinical research through to clinical drug development

  • Highly effective teamwork and interpersonal skills

  • Exceptional written and verbal communications skills.

  • Functional group advisor/go-to person.

  • Able to assess risk & develop contingency plans.

  • Serves as subject matter expert and functional group advisor on science, technology, methods, etc.


The starting compensation for this job is a range from $194,000 - $268,400, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and the where the job is performed.

Final individual compensation will be decided based on demonstrated experience.

For more on benefits, please visit our

Eligibility for specific benefits listed on our BMS Careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.