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Job Details

Merck & Co, Inc

Director, Chemical Biology

Science and Research

Clinical Research Director


Cambridge, Massachusetts, United States

Job Description

Become a part of the cutting edge and highly innovative Chemical Biology and Discovery Chemistry departments. Using robust scientific methodology, bleeding edge chemistry, and state-of-the-art instrumentation and automation, we collaborate to discover the next medical breakthrough. To achieve our goal, we focus on delivering novel mechanisms into our pipeline, expanding druggable space, and the pursuit of detailed knowledge of the mechanism of action for our key pipeline assets. We partner with multiple functional groups to complement capabilities, accelerate discoveries, and advance the best drug candidates into the clinic for significant unmet medical needs.

Passion for thinking outside the box is critical in Chemical Biology as a field and to the success of enabling drug discovery programs. We are therefore seeking an exceptional scientist and mentor for a Director role the Chemical Biology group in the Discovery Chemistry organization within our company’s Research Laboratories.

The individual will join the Chemical Biology Leadership Team and will have broad range of responsibilities across strategy, talent, and pipeline. The Director will build strong relationships within Discovery Chemistry and across Quantitative Biosciences, Genetics and Biomarker Sciences, and Therapeutic Area Biology to translate new advances in technologies into pipeline impact towards delivering innovative therapeutics. The incumbent will coach, mentor, and support career development of a team of talented scientists. In addition, the incumbent will participate in departmental and network-wide activities such as recruiting, resource-management and external engagement, as well as communicate with governance committees and external collaborators. Finally, the incumbent will be accountable for driving employee engagement within Discovery through the promotion of diversity and inclusion initiatives and supporting a culture of innovation.


  • Ph.D. or equivalent with five (5+) or more years relevant experience in Chemical Biology, Discovery Chemistry or a related discipline in a pharma, biotech or academic setting (B.S. or M.S. with 10+ years relevant experience)

Required Experience:

  • Exceptional understanding of biology concepts and chemical application to solve biological problems
  • Experience in synthetic chemistry
  • Highly self-motivated, creative, and critical thinking to solve complex technical and scientific problems with excellent attention to detail
  • Ability to build strong, inclusive relationships in highly collaborative, multidisciplinary teams to effectively drive early drug discovery initiatives
  • Project team leadership: setting strategy and driving programs to key decision points
  • Communicating effectively in a highly productive multi-disciplinary environment
  • Capable of prioritizing deliverables among multiple simultaneous projects
  • Robust publication record
  • Strong organizational and time management skills

Preferred Experience and Skills:

  • Experience in small molecule drug discovery and in early target discovery and validation
  • Professional development and/or mentorship of others

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.


For positions located in the United States and Puerto Rico – Subject to applicable law, all new hires (including internal transfers) must demonstrate that they are fully vaccinated against COVID-19 or that they qualify for a medical or religious exemption to this vaccination requirement. New hires (including internal transfers) to a position that, as determined by the Company, requires routine collaboration with external stakeholders (such as roles in health services or customer-facing commercial or research-based roles) (“Customer-Facing Role”) who are not vaccinated must qualify for a medical or religious exemption and be in a position that the Company determines can accommodate unvaccinated employees without causing an undue burden to business operations. If, following dialog with the candidate as appropriate, it is determined that the candidate either a) does not qualify for a religious or medical exemption or, b) for candidates applying for Customer-Facing roles, it is determined that allowing the candidate to work without vaccination would cause an undue burden to the Company, the candidate will be ineligible for hire or transfer, or any offer of employment or transfer (if applicable) will be revoked. Please note that notwithstanding the approval of any reasonable accommodation, the Company reserves the right to monitor, modify, or revoke any such accommodation if it is determined, following dialog with the employee, that the accommodation is no longer effective or results in an undue burden to the Company.

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US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:




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Flexible Work Arrangements:


1st - Day

Valid Driving License:

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Number of Openings:


Requisition ID:R219461