Manager Data Science - Novartis - Navigate Biopharma, Carlsbad, CA

1 in 5 men and 1 in 6 women worldwide develop cancer during their lifetime, and far too many will lose their battle every year. At Navigate we envision a disease free world – our talented and passionate team is at the forefront of enabling drug development by using transformative science to deliver high quality, world class clinical biomarker solutions so we can one day realize that vision. <br><br>Join us on our journey to turning innovative treatment ideas into reality to improve and extend patient lives across the globe. Navigate Biopharma, a fully owned subsidiary of Novartis, provides assay development, clinical trial testing, and companion diagnostics services to companies in the precision medicine field. At present, Navigate supports 100+ clinical trials from 30+ pharma, biotech, and diagnostic companies, including 8 of the top 15 oncology companies globally.<br><br>Develops and contributes to the development and validation of data processing applications and performs data analysis activities required for the successful launch and execution of biomarker solutions in CLIA lab across technology applications. Responsible for leading a team of data science and bioinformatics team members. Designs, creates, executes, and formulates and integrated analytical approach for, AI and machine learning algorithms and automate processes for reducing effort and time for repeated use. Manage & empower team and provide guidance and operational aspects <br><br>Your responsibilities:<br><br>• Strong knowledge and understanding of statistical methods such as meta-analysis, Bayesian methods, bagging/boosting, variable selection methods (e.g., PCA, elastic net, random forest), design of experiments<br>• Strong programming skills in R. Demonstrated knowledge of data visualization and exploratory analysis.<br>• Familiarity with statistical and analytical methods for genetics and omics data analysis, and working knowledge of high dimensional exploratory biomarker platforms (e.g., next generation sequencing, flow cytometry, etc.)<br>• Experience in the application of bioinformatics pipeline development<br>• Serves as subject matter expert for software development and/or statistical analysis activities of clinical testing from concept to completion.<br>• Research and co-develop with supervisor new algorithms, methods, statistical models and business models and providing insight into structured and unstructured data, support the evaluation of the need of technology and novel scientific software, visualization tools and new approaches to computation to increase efficiency and quality<br>• High level of independence working on multiple projects.<br>• Critical thinking, initiation, management of success and failure of complex projects.<br>• Develops timelines and work flows to ensure successful execution of assigned projects and processes.<br>• Makes recommendations for scientific processes and drives projects.<br>• Contributes to the meeting of functional goals and resolution of varied issues under general direction<br>• Identifies obstacles and recommend solutions or improvements to existing departmental, or functional, scientific or technical processes or programs.<br>• Independently prioritizes multiple projects and work load. Will provide direction to more junior associates in the lab.<br>• Drives the launch of new application software and manages projects of strategic importance.<br>• Provides key scientific knowledge to drive success of strategic activities. Effects of decisions are long-lasting and heavily influence the department goals. <br><br><br>[#video#https://www.youtube.com/watch?v=Mo1vwtVPVA0{#400,300#}#/video#]