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Research Scientist – Hematology and Gene & Cell Therapy

Science and Research

Research and Development



Cambridge, Massachusetts, United States

5600! That’s the number of the associates in the Novartis Institutes for BioMedical Research (NIBR). NIBR is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.<br><br>We are seeking a highly motivated, collaborative, and curious Research Scientist to join the Hematology Gene Therapy Team within NIBR’s Immuno-Oncology & Hematology (IOH) Research Department. We are dedicated to innovating the next generation of ex vivo engineered Hematopoietic Stem Cell (HSC) therapies for genetic disease. The discoveries we make can contribute directly to improving efficacy and accessibility of gene therapies to patients. As a key contributor in a dynamic, multidisciplinary team, you will be involved in the design and execution of in vitro and in vivo studies enabling the validation and development of innovative cell therapy platforms, genome editing technology, and novel modes of delivery. <br><br>Your responsibilities include, but are not limited to:<br>• Conduct and optimize experiments independently; record, interpret, and communicate data promptly. <br>• Establish and perform in vitro cell based assays to support gene therapy research with hematopoietic cell lines and primary HSCs. <br>• Utilization of gene modification and editing tools including CRISPR, lentivirus, and AAV, etc.<br>• Follow IACUC protocols and standard operating procedures (SOPs) to perform in vivo pharmacology study.<br>• Present data in meetings and contribute to discussion<br>• Self-motivation, ability to work independently when needed, as well as a passion for working in an interdisciplinary, collaborative research environment.<br><br>[#video#{#400,300#}#/video#]