Postdoctoral Research Fellow – Organic Synthesis and High-Throughput Experimentation (HTE) Applied to Chemical Biology

Job Description

Organic Synthesis and High-Throughput Experimentation (HTE) Applied to Chemical Biology

New hires working in our US & Puerto Rico locations will be required to demonstrate that they have been fully vaccinated for COVID-19 or qualify for a medical or religious exemption or accommodation to this vaccination requirement, subject to applicable law.

Be a part of the legacy: Postdoctoral Research Fellow Program

Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

We are seeking a highly motivated and skilled synthetic chemist to join Boston Discovery Chemistry as a postdoctoral fellow. The postdoc fellow will be responsible for developing and applying new methods toward the synthesis of biological probes, heterobifunctional degraders, and other tools molecules of relevance to chemical biology. This role will rely heavily on the use of high-throughput experimentation (HTE) and will collaborate with the HTE, Chemical Biology, and Targeted Protein Degradation (TPD) groups in Kenilworth, including travel where appropriate. The successful fellow must have excellent interpersonal and communication skills to facilitate collaboration, and will be expected to deliver high-quality peer-reviewed publications and present externally at chemistry conferences.

Responsibilities include but are not limited to:

• Lead the invention and optimization of new methods for the preparation of tool molecules of relevance to chemical biology
• Learn and apply state-of-the-art enabling technologies, specifically HTE
• Disciplined decision making, strategic thinking, and creative problem solving
• Network with colleagues and build effective working relationships with adjacent functional areas, including HTE, Chemical Biology, TPD, analytical research, and modeling/informatics
• Present ideas and results both internally (our company) and externally (conferences)

Education Minimum Requirement:

• Candidates must currently hold a PhD in chemistry or a related discipline OR will receive a PhD by Fall 2022.

Required Experience and Skills:

• Experience of all techniques associated with modern organic synthetic chemistry, including the synthesis, purification, and characterization of chemical compounds on small (milligram) and medium (gram) scale
• Proven ability to complete research projects, as evidenced by peer-reviewed publications and conference presentations
• Strong leadership, mentorship, problem solving, and troubleshooting skills
• Ability to independently design experiments, interpret data, and incorporate data into new designs leading to successful experimental outcomes
• Functions well within multidisciplinary teams, and possesses outstanding oral and written communication skills

Preferred Experience and Skills:

• Experience in the field of catalysis and reaction optimization
• Demonstrated aptitude for learning and adopting new technologies and tools
• Anticipates the needs for contingencies, and plans alternative strategies as a means of risk management
• Conceptualization of new ideas and project directions
• Additionally, technical knowledge in chemical biology, specifically protein degradation, would be beneficial

Resume keywords for recruiting team:

catalysis, synthesis, high-throughput experimentation, chemical biology, protein degradation

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

MRLpostdoc

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

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Flexible Work Arrangements:

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Requisition ID:R154554