Senior Principal Scientist Fibrosis Drug Discovery Biology (R1553598-en-us)
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immuno-science and fibrosis.
Join us and make a difference. We hire the great people and provide them with a work environment that places a premium on diversity, integrity, collaboration, and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.
Lead an exploratory drug discovery program for the identification of a novel anti-fibrotic therapy in collaboration with chemistry, lead optimization, and translational research teams.
Utilize human and animal model data with the aim of identifying and/or validating new pathways and potential drug targets for fibrosis.
Develop and validate novel in vitro biochemical, molecular and/or cell based assays utilizing the latest technologies to shorten the time required for drug target validation and to provide support to the Fibrosis Discovery pipeline.
Maintain knowledge of the current literature, propose novel concepts and targets.
Publish in scientific journals and present in scientific meetings.
PhD, MD-PhD, MD preferred.
Pharmaceutical industry experience (5-7 yrs) strongly preferred, or equivalent experience in academia leading an independent research program/laboratory; outstanding research track record and publication history in the relevant field required.
Expertise in fibrosis related conditions such as idiopathic pulmonary fibrosis; expertise in lung biology preferred. Strong background in immunology and cellular wound healing processes a plus.
Skills in biochemistry, molecular biology, cell biology in vitro biochemical assays and/or receptor pharmacology.
Experienced in the handling and use of primary cell cultures and development of complex cell systems. Experience handling animal models is a plus, but not required.
Knowledge of the drug discovery process. Ability to identify potential new targets in the fibrosis area based on analysis of internal data, literature and or combination of both. Experience leading a drug discovery program a plus.
Evidence of working within a competitive environment, being a team player and a commitment to scientific excellence.
Excellent verbal and written communication skills as indicated by a track record of publications and presentations at scientific conferences.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
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