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Job Details

Bristol Myers Squibb

Principal / Senior Principal Scientist- DMPK (R1556026-en-us)

Science and Research




Princeton, New Jersey, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Summary

We seek an innovative, self-motivated, exceptional scientist to join our Drug Metabolism and Pharmacokinetic (DMPK) department at our Princeton, NJ site. This role will be at the Principal or Senior Principal level depending on the selected candidate's experience and background. The role works with multiple disciplines in drug discovery to achieve in vivo proof-of-concept for target validation, influence drug designs in lead optimization, and ultimately identify drug candidates for advancement into the clinic. The selected candidate will have opportunities to work on multiple modalities, including small molecules, biologics, and antibody-drug conjugates, and develop deep scientific expertise in drug hunting.

Key Responsibilities

  • Provide strategic and scientific leadership as a DMPK representative in discovery teams to support programs

  • Independently design and conduct DMPK and pharmacokinetic-pharmacodynamic (PK-PD) studies; interpret and present the data to project teams

  • Proactively address project issues and apply model-based approaches to integrate pharmacology and toxicology data for decision-making

  • Effectively represent DMPK function and articulate DMPK-related issues and resolutions at project review and portfolio governance meetings

  • Actively engage and collaborate with cross-functional colleagues within or outside the project teams

Qualifications & Experience

  • Ph.D. in pharmacokinetics, drug metabolism, pharmacology, or related discipline with a minimum of 3 years of experience or MS with 10+ years of industrial experience

  • Broad understanding of ADME and PK/PD principles and experience in supporting drug discovery as a DMPK representative

  • An agile learner with scientific curiosity and strong problem-solving skills

  • Excellent interpersonal, organizational, oral/written communication skills

  • A strong team player with ability to collaborate and build trustworthy relationships with other disciplines for idea generation, issue resolution and program advancement

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.