Scientist, Cell Sciences

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

This position will join the Cell Sciences Team at Bristol Myers Squibb supporting Cell Therapy and Immune Oncology by managing and maintaining the Cell Core research cell banks, developing novel cell-based reagents and recombinant proteins to advance Research projects. This role will involve supporting and managing across all of these aspects, requiring a thorough knowledge of cell culture, flow cytometry, gene engineering and excellent communication and collaborative skills.

This role is a bench-facing research position primarily focused on delivering cells for in vivo assays, engineered cell line generation, and proving guidance to project teams for which cell based reagents will best fit their program needs. The candidate will be expected to work under minimal supervision to design and troubleshoot experiments and effectively record, present, and communicate results to multidisciplinary project teams.

Responsibilities

• Cell line sourcing, expansion, testing, and banking. Data entry and maintenance of cell resources catalog and delivery of resource requests from that catalog.

• Recording the activities in ELN and databases, work on the record compliance and quality improvements.

• Scale-up mammalian cell line cultures in a variety of formats (TC flasks, shaker flasks, other devices), transient/stable expression of recombinant protein.

• Construction of recombinant and genome-engineered cell lines: transfection/transduction/gene editing of host cell lines (with CRISPR/Cas9 and viral delivery), selection, sorting, cloning and assays to select desirable clones or pools of clones.

• Flow cytometry, analytical and sorting.

• Participation in cross-functional teams as a key expertise resource to provide knowledge and guidance for design of engineered cell lines reagents to support research projects and provide cell culture methods. Presenting results, collaboration with Project Leads and Project Management on timelines.

• In collaboration with Lab Operations, Supply Chain, and outside resources upkeep of laboratory infrastructure (instruments and supplies), planning, budgeting, maintenance.

• Researching, testing, adapting, and outsourcing of new technologies to augment Cell Sciences deliverables to research projects and teams.

• Communicate effectively, foster teamwork, and contribute to project strategy discussions

Skills/Knowledge Required:

• Expertise in mammalian cell culture including single cell cloning.

• Experience with genome engineering via transfection/transduction, familiarity with CRISPR/Cas9.

• Independence in flow cytometry/cell sorting

• Familiarity with principles of cellular and molecular immunology.

• Previous hands-on experience with various cell-based assays including, but not limited to, molecular cloning, proliferation, apoptosis, cell cycle analysis, western blotting, FACS, and quantitative PCR.

• Experience with scientific and data analysis programs including FlowJo, Microsoft Excel and PowerPoint.

• Planning skills to execute on multiple work streams and provide timely and prioritized results.

• Trouble shooting and problem-solving skills to investigate technical and scientific questions.

• Demonstrated ability to work effectively in a collaborative team setting.

• High attention to detail and ability to work in a rapidly changing environment, with frequent changes of priorities.

• Outstanding visual, oral and written communication skills

Basic Qualifications

Bachelor's Degree 5+ years of academic / industry experience

or

Master's Degree 3+ years of academic / industry experience

or

PhD + No experience required

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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