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Bristol Myers Squibb

Scientist, Genomics (R1557499-en-us)

Science and Research

Scientist

Yearly

No

Cambridge, Massachusetts, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. We are passionate about making an impact on the lives of patients through research. This open position offers the opportunity to join a vibrant and collaborative research community striving to find new disease targets and develop innovative therapies.

We seek a highly self-motivated, goal-oriented genomics scientist with broad experience in the application of genomic tools to understanding disease biology. Experience in cancer genomics is highly preferred. The position is in Research and Early Development and sits within the Mechanisms of Cancer Resistance Thematic Research Center. The role includes implementing and running advanced genomics technologies (such as single-cell RNA seq, spatial transcriptomics) with potential to implement functional genomics assays as part of highly collaborative project team. The work will include diverse projects that will impact multiple areas including target ID, asset progression and translational research. There will also be responsibility for project management, training and overseeing other team members, and standard NGS workflows.

The successful candidate will need to demonstrate a track record of deep knowledge in modern genomics, molecular biology, and next generation sequencing. The candidate will also need to exemplify a consistent drive to learn and apply new technologies to biology-driven questions. The position requires constant scientific engagement and growth, and offers opportunities for career progression.

Responsibilities

· Develop, implement, and run novel genomic assays such as single cell DNA/RNA-seq and spatial transcriptomics.

· Carry out research projects with minimal supervision.

· Manage and support various research projects and collaborations across the early target ID, asset progression and translational research space.

· Optimize existing genomics methods or develop new protocols.

· Supervise and/or maintain NGS workflows and run NGS assays.

· Collaborate with Informatics and Predictive Sciences colleagues.

· Train and assist other team and site members.

· Take initiative in experimental design.

· Communicate project status and results clearly both within the group and across teams.

· Organize, track and progress projects in a timely fashion.

· Maintain lab notebooks; compile data and written experimental instructions.

· Mine published research works to support experimental efforts.

Highly preferred expertise: Deep expertise in cancer genomics, biomarker identification, in vivo studies, donor sample handling, and automation. Extensive experience in single cell RNA-seq in plates, droplets or microwells, and/or spatial transcriptomics, Nanostring DSP, or other multiplexed transcriptomics methods. Experience with cancer model development and functional genomics. Familiarity with Jira, LIMs, confluence or other project management solutions.

Requirements

The successful candidate must have:

· B.S./ M.S. in Molecular/Cell Biology, Genetics, Genomics, Biochemistry or a related field with at least 5-10 years of extensive genomics experience in an academic or industry setting; OR, a Ph.D. in genetics, genomics, oncology or a related field with a proven applied genomics track-record.

· A deep understanding and hands on experience in genomics techniques and related technologies.

· A successful track record in the genomics or NGS space with demonstrated accomplishments.

· Experience successfully completing multiple projects in a dynamic and fast-paced environment.

· Strong communication skills and experience managing collaborations across multiple groups and teams.

· Broad hands-on experience in molecular biology methods relevant to genomics. Experience in advanced cell and molecular biology technique is essential.

· Excellent organizational and time-management abilities are required.

· Ability to work effectively in a highly collaborative environment.

Other preferred background experience: Direct hands on experience in at least one of the following areas: Custom RNA/DNA isolation, high-throughput molecular assays, automation, NGS library construction, familiarity with data analysis and data interpretation, experience working with FFPE and clinical samples, expertise in cell culture and/or separation technologies such as FACS, and microfluidics, or cancer model development.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.