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In Vivo Research Scientist, Ophthalmology (344731BR)

Science and Research




Cambridge, Massachusetts, United States

256 million people worldwide are affected by glaucoma and age-related macular degeneration (AMD), two of the leading causes of vision loss in older adults. As the global population ages, eye diseases are projected to significantly increase over the coming decades. <br><br>At the Novartis Institutes for BioMedical Research (NIBR), we are focused on discovering therapies for glaucoma, AMD, and other blinding eye diseases.<br><br>We are seeking a creative and collaborative research scientist to join our Ophthalmology department to help discover new therapies for ocular diseases. A successful candidate in this position will have a hands-on role focusing on ocular disease model development and characterization with the opportunity to reveal new biology leading toward innovative therapeutic candidates. The knowledge generated will directly contribute to driving discovery of new therapies for patients with blinding diseases.<br><br>Your responsibilities:<br><br>•Plan and perform in vivo pharmacology experiments, then analyze, summarize, and clearly present that data to inform project team decisions.<br>•Extensive animal handling (basic manipulation, restraint and injections)<br>•Experience with techniques such as Western blot, qPCR, immunofluorescence, etc. <br>•Establish and validate in vivo models of ocular disease that will be used to develop new drugs<br>•Apply creative solutions toward solving experimental challenges.<br>•Maintain an open and collaborative mindset, required to effectively operate in a highly matrixed team.<br>•Authoring, delivering and presenting study reports to project teams to drive key decisions.<br><br>[#video#{#400,300#}#/video#]