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Principal Scientist (Psychiatry) (347895BR)

Science and Research




Cambridge, Massachusetts, United States

60 million. <br>That’s how many adults in the US experience mental illness in a given year.<br><br>The Neuroscience Department with Novartis Institutes for BioMedical Research (NIBR) is dedicated to discovering and developing groundbreaking therapies for serious diseases of the nervous system. The psychiatry team is focused on applying leading edge approaches to develop new therapeutics for these psychiatric diseases. This position is an opportunity to help create and advance such life-changing therapies.<br><br>As a new Principal Scientist in the Neuroscience Psychiatry group, you will have the opportunity to reimagine medicine by developing innovative treatments that can improve lives and health of patients suffering from psychiatric disease. You will join a vibrant scientific community and collaborate with other scientists within the neuroscience division as well as across other NIBR disciplines and platforms, including genetics, therapeutic discovery, global discovery chemistry, data science, biomarker development, and translational medicine.<br><br>Your key responsibilities:<br><br>• You will identify key unmet needs in the psychiatric disease space and propose novel therapeutic solutions<br>• You will implement novel approaches for identifying circuit dysfunction in animal models of disease and identify therapeutic strategies<br>• You will initiate and lead drug discovery efforts on high-value targets, applying innovative approaches and technologies <br>• You will develop hit-finding and lead-optimization strategies for relevant small molecule or biologic programs<br>• You will lead a matrixed team of highly talented and multi-disciplinary scientists responsible for small molecule and / or biologic screening, prioritization and validation <br>• You will be responsible for leading the team to achieve deliverables and meet aggressive timelines<br><br>