Senior Research Scientist
Attention NJ Applicants: In April 2020, our Company announced plans to consolidate our New Jersey campuses into a single New Jersey headquarters location in Rahway, NJ by 2023. Therefore, the NJ work location for this role will be temporarily based and the exact timing of the departmental move to Rahway, NJ will be communicated at a future date.
The Screening & Compound Profiling Group is seeking a highly motivated Scientist with a background in CRISPR gene knockout technology in our Quantitative Biosciences Department at our Research Laboratories in Kenilworth, NJ. Ideally you will have experience using CRISPR for gene knockout, with a solid understanding of how to optimize editing conditions. Your primary responsibilities will be to support arrayed CRISPR screening in collaboration with other members of the group and scientists from across the company. The ideal candidate will have experience with a variety of cell-based assays, with an emphasis on complex cellular models and high-content imaging for functional genomics. Knowledge and understanding of miniaturized assays (384 well) and downstream detectors ranging from standard luminescence-/fluorescence-based readouts to imaging and cell-microarray based platforms is desired. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.
Team member with Integrity | Precision | Accomplishment | Motivational Ambition | Respect | Inclusion
Experienced screening with CRISPR gene editing in pooled or arrayed formats and experienced in validating and optimizing conditions for CRISPR gene editing.
Experienced with mammalian cell culture and running cell-based assays in multi-well format.
Experienced with transfection techniques for mammalian cells in high throughput (lipid transfection or electroporation).
Collaborate with Project teams across the company to develop innovative approaches to target-based and phenotypic screening for small molecule discovery efforts.
Solid understanding of data analysis workflows and statistics. Experienced with Microsoft Excel and Graphpad Prism.
CRISPR gene editing of mammalian cells.
Experienced working with cell lines in multi-well plates.
Experience with transfection of mammalian cells.
Molecular biology methods (PCR, cloning, etc).
Understand basics of data analysis.
BS degree with 3+ years in CRISPR gene editing and in vitro assay experience; MS degree with 0+ years
We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are …
We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for …
Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.
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Expected salary range:$96,700.00 - $164,500.00
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