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In Vivo Senior Scientist (BS/MS)

Science and Research



Cambridge, Massachusetts, United States

50 million! That is the number of people who are currently affected by neurodegenerative diseases worldwide. Our Neuroscience department is developing new therapies for neurological disorders, and we would like you to join our team! In this role, you will establish and optimize translational biochemical and molecular pharmacodynamic readouts for preclinical studies to support our drug discovery programs. A major focus for you will be the establishment and utilization of preclinical in vivo models.<br><br>What you’ll be doing: <br>Your responsibilities include, but are not limited to:<br>• Developing and implementing inducible, surgical, and transgenic rodent models<br>• Designing, coordinating, and executing target engagement and efficacy studies to evaluate novel therapies<br>• In vivo model techniques including dosing, sample collection, and stereotaxic surgery<br>• Ex vivo investigation into pharmacodynamic readouts and novel biomarkers from a range of preclinical samples such as tissue, plasma, and CSF<br>• Quantitative data analysis utilizing multiple platforms and stringent statistical methods<br>• Sharing results with key stakeholders up to department-wide level<br>• Communication and collaboration across the organization<br>• Literature exploration, thinking creatively, and implementing innovative technologies<br><br>What you’ll bring to the role: <br><br>• B.S. degree or equivalent in biology, pharmacology, neuroscience, or a similar discipline<br>• At least 5 years of pharmaceutical industry or biotechnology research experience <br>• Strong scientific background in in vivo pharmacology and neuroscience<br>• Exemplary organizational and record-keeping skills<br>• Excellent communication with ability to present data to project teams <br>• Ability to thrive in a fast-paced drug discovery environment with positivity and persistence regardless of challenges<br><br>Preferred Qualifications: <br>• M.S. degree in in biology, pharmacology, neuroscience, or a similar discipline<br><br>Why consider Novartis?<br><br>We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you are given opportunities to explore the power of digital and data. Where you are empowered to risk failure by taking smart risks, and where people who share your determination to tackle the world’s toughest medical challenges surround you.<br><br>We are Novartis. Join us and help us reimagine medicine!<br><br>The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.<br><br>Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams, representative of the patients and communities we serve.<br><br>Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1 [Register to View] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.<br><br>Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination.<br><br>As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to