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Job Details


Bristol Myers Squibb

Senior Scientist / Principal Scientist- Bioanalytical

Science and Research

Scientist

Yearly

No

Princeton, New Jersey, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

Nonclinical Research and Development (NCRD) is an integrated function with responsibility for characterizing nonclinical safety and disposition characteristics of the entire BMS Research and Development pipeline programs, with critical role from early discovery to submission of marketing authorization applications. We utilize our deep expertise in toxicology/pathology, ADME, PK/PD, biopharmaceutics and Bioanalytics in all modalities (small and large molecules, cellular therapies and other novel modalities) to collaborate with peer R&D functions to identify and solve issues, discover high quality drug candidates, enable their clinical development and successful marketing authorizations across the globe.


Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Job Profile:

We are seeking a highly enthusiastic, self-motivated, exceptional scientist to join the bioanalytical research group in drug discovery that is part of the Pharmaceutical Candidate Optimization (PCO) department in Lawrenceville, NJ. PCO encompasses broad scientific expertise in DMPK, toxicology, pharmaceutics, and focuses on advancing new targets in drug discovery. The successful candidate will work within a team of bioanalytical scientists that collaborate across the PCO disciplines in collaboration with discovery biology and chemistry. The candidate is expected to have an in-depth understanding of qualitative and quantitative approaches using chromatography and high-resolution mass spectrometry with advanced data interpretation skills. This position will have responsibilities for defining and executing bioanalytical strategies best suited for quantitation of small molecule drugs and endogenous small molecules. Additionally, the successful candidate will be directly involved in designing and executing metabolomics profiling studies in support of Drug Discovery and Development efforts.

Job Responsibilities:

The successful applicant will be primarily responsible for the following:

  • Plan and execute metabolomics studies for biomarker discovery, model characterization, etc. in support of Drug Discovery and Development. Utilize and further develop the in-house generated metabolomics platform, which includes a custom-developed and supported data processing software.

  • Serve as a point of contact for future metabolomics studies including outsourcing efforts.

  • Assay-development and quantification of small molecule drugs and endogenous small molecules from biological samples (plasma/serum, tissue homogenates, DBS, etc.) using LC-MS/MS and HRMS.

  • Expert operation of Triple Quad mass spectrometers (Waters, Thermo, Sciex) and high-resolution instruments (Thermo QEs). Data processing, data interpretation and reporting.

  • Collaborate in a multidisciplinary research environment to address bioanalytical issues related to discovery programs and provide input into bioanalytical strategies.

  • Represent the department on project teams and present data at internal department and/or other company meetings, as well as external conferences.

  • Maintain good laboratory practices and documentation (Electronic Lab Notebook).

Basic Qualifications:

Senior Scientist

  • Bachelor's Degree 7+ years of academic / industry experience

or

  • Master's Degree5+ years of academic / industry experience

or

  • PhD2+ years of academic / industry experience

Principal Scientist

  • Bachelor's Degree 8+ years of academic / industry experience

or

  • Master's Degree6+ years of academic / industry experience

or

  • PhD4+ years of academic / industry experience

Preferred Qualifications:

  • Ph.D. or M.Sc. degree in analytical chemistry, biochemistry or related discipline with at least 10 years of relevant experience, with emphasis on metabolomics and/or quantitative mass spectrometry for the Principal Scientist Level or at least 5 years of relevant experience with emphasis on metabolomics and/or quantitative mass spectrometry for the Senior Scientist Level.

  • Previous experience with metabolomics.

  • Hands-on experience with different sample preparation procedures such as protein precipitation, liquid-liquid extraction, solid-phase extraction, etc.

  • Hands-on experience with Triple Quad mass spectrometers (Waters, Thermo, Sciex) and High-Resolution mass spectrometers (Thermo QEs).

  • Ability to independently diagnose and solve complex technical and scientific problems.

  • Ability to troubleshoot and perform minor instrument repairs to maintain highest performance and minimize downtime.

  • Self-motivated with excellent communication, organizational and interpersonal skills. Able to effectively manage and interface with others in a matrix team environment.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.