Scientist Biochemistry

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us

Position: Scientist – Biochemistry/Biophysics

Location: Brisbane, CA

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Immunology, Cardiovascular, Fibrosis, and Global Health (ICFG) Thematic Research Center (TRC) at BMS is one of the fundamental Research and Early Development (R&ED) units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS’s internal invention of engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. We work closely our R&ED colleagues in clinical and non-clinical development, project leadership, translational medicine, and informatics to advance therapies based on a deep understand of causal human biology. Further, we collaborate across the biopharmaceutical ecosystem to establish partnerships that complement our internal expertise.

Position Summary

We are seeking an experienced, knowledgeable, and self-motivated Scientist to join our biology team within the company’s research division. Key accountabilities in this position include development of novel biochemical and biophysical assays that enable a mechanistic understanding of small molecule modulators, as well as providing experimental support and direction for existing development strategies. This position would entail ~70% laboratory presence with the rest of the time spent in other activities.

Key Responsibilities

• Characterize small molecule modulators using biochemical and biophysical assays to support hit-lead, lead-op, MOA, and translational efforts.

• Develop and implement novel biochemical and biophysical assays to investigate how potential therapeutic agents modulate the targeted protein function.

• Responsible for protein purification of needed reagents.

• Plan and perform critical-path experiments in a manner consistent with the timelines and objectives of various therapeutic program teams.

• Collaborate with cross-functional teams in Research to provide timely and actionable study results.

• Communicate results efficiently to the project teams.

• Maintain a detailed and well-organized record of experiments

Qualifications & Experience

Basic Qualifications:

• Ph.D. in Biochemistry or Biophysics

or

• Master with 3+ years industry experience

or

• Bachelor with 5+ years industry experience

Preferred Qualifications:

• Direct experience in executing biochemical/biophysical assays for small molecule drug discovery to support hit identification, hit-to-lead, and lead optimization activities.

• Hands-on experience with biophysical methods such as SPR, DSF and ITC and biochemical methods such as stopped-flow kinetics.

• Protein chemistry technical skills including recombinant protein expression and purification, labelling, and characterization; native tissue protein purification desired

• Steady-state and transient kinetics experience

• Basic knowledge of biological data analysis tools (i.e., GraphPad Prism)

• Strong problem-solving skills, ability to develop new techniques and methodologies.

• Excellent organizational and time management skills.

• Must be self-motivated, detail-oriented, collaborative, and able to work effectively in a multidisciplinary environment.

• Good communication and presentation skills.

The starting compensation for this job is a range from $97,000 - $123,000, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

Why You Should Apply

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.