Senior Scientist - Translational Research

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Excited to grow your career?

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

About Bristol-Myers Squibb

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, immunology, hematology, and cardiovascular disease.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration, and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Location

Cambridge, MA

Position Summary

We are seeking an individual with oncology translational research and early clinical development experience to join the Translational Research (TR) team within the Mechanisms of Cancer Resistance Thematic Research Center (MoCR TRC) at Bristol-Myers Squibb in Cambridge, MA. The qualified candidate is highly motivated, collaborative, creative, and can work across a highly matrixed organization to advance programs from lead optimization, through IND enabling activities, and ultimately clinical Proof of Concept.

This individual will be responsible for developing and executing translational research and biomarker strategies for MoCR TRC programs. This individual will bring scientific and technical expertise with emphasis on oncology biomarkers, early clinical development, technology platforms commonly used for biomarker analysis, and cross-functional matrix management.

Position Responsibilities

• Develop and execute translational biomarker strategies for programs within the MoCR TRC with a focus on target engagement, pharmacodynamics, mechanism-of-action, patient/indication stratification/selection and rational combination partner selection.
• Partner with key cross-functional stakeholders including clinical trial physicians, clinical scientists, clinical pharmacologists, biospecimen sample managers, clinical operations, drug discovery biologists and early development leads to execute and deliver your translational and biomarker strategy
• Analyze, synthesize, and communicate biomarker data from early phase clinical development trials
• Support the authoring of essential documentation including clinical trial synopses, clinical trial protocols, CSRs, and internal governance communications.
• Ensure that biomarker plans meet established program standards (within budget, on schedule, compliance, etc.)
• Communicate key biomarker program information, risks, and milestones, within team and continues to define, revise and progress biomarker plans as projects progress

Desired Experience

• Ph.D. plus postdoctoral training in cancer biology, immuno-oncology, or equivalent advanced biology degree, with some (2-4 years) industry experience ideally supporting translational research and biomarker activities for a clinical stage program
• Experience in the discovery and implementation of pharmacodynamic and predictive biomarkers using preclinical models
• Intimate knowledge of and extensive hands-on experience with relevant molecular and cell biology techniques along with biochemical and cell-based assays
• Experience in the field of immuno-oncology is a plus
• Excellent interpersonal skills as well as verbal and written communication skills
• Ability to recognize, articulate, and accept calculated risks to make informed decisions
• Comfortable working in a fast-paced environment where speed is paramount
• Demonstrated experience in appropriate application of various scientific technologies into translational research strategies
• Demonstrated ability to effectively influence stakeholders in a dynamic, matrixed organization

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.