Inhalation Toxicology Research Scientist
Leidos is seeking an experienced Research Scientist to perform Inhalation Toxicology Research in support of biomedical research in the Environmental Health Effects Laboratory (EHEL) at the Naval Medical Research Unit Dayton, OH. The successful candidate will serve as Project Lead in cell-based, animal use research studies on environmental and occupational exposures to identify health effects before health and operational performance is compromised in the warfighter. Cell-based studies include the use of in vitro and ex vivo models, bacterial systems and molecular assays to address toxic effects and mechanisms. Research efforts will require assistance with interrogatories, medical and scientific authoring and editing of research proposals, animal use protocols, technical and scientific reports, responses to grants and funding calls; scientific management, coordination of technical review meetings and the preparation and presentation of point papers, technical reports, and other briefings resulting from these meetings, preparation and support of technical summaries and publications resulting from research activities, support in development of Institutional Animal Care and Use Committee (IACUC) protocols for animal research; presentation of research findings at scientific meetings / professional conferences; writing, reviewing, editing, and submitting peer-reviewed articles and technical reports.
Work with a diverse team of scientists, including toxicologists, engineers, neuroscientists, chemists, psychologists, animal behaviorists and biologists, to accomplish the mission of understanding the health effects of operating in military settings.
Design and conduct scientific research on the toxicological effects of exposure to chemicals/mixtures, often in combination with extreme environmental hazards or stressors, to include temperature, humidity, altitude, vibrations, and noise, and/or physical demand.
Utilize animal models to evaluate the short- and long-term health and performance effects of acute and chronic exposure to chemicals, mixtures, environmental hazards and stressors, and/or physical demand.
Provide scientific expertise in the field of inhalation toxicology regarding all organ systems, including neurological/cognitive and developmental and reproductive effects.
Identify, devise, propose and execute military relevant studies and collect data from animal subjects (primarily rodent)
Develop appropriate exposure systems, including analytical techniques for identifying toxicants and/or aerosols.
Contribute substantially to the design and building toxicant generation and other exposure systems.
Perform risk assessments based on collected toxicological data.
Assist other investigators in the design and execution of research protocols on inhalation toxicology and environmental exposure issues of interest to the Navy.
Operate and maintain standard and specialized laboratory equipment.
Assist and educate entry level research assistant personnel in the understanding and performance of their duties.
Collect pulmonary/respiratory data, or other appropriate endpoints, from animal subjects following exposure.
Perform statistical analyses using SigmaPlot, Statistical Package for the Social Sciences (SPSS) or Statistical Analysis Software (SAS). Examples of the typical analyses required for successful performance include T-tests, Chi-Square, Analyses of Variance, Multivariate Analyses of Variance, analyses of covariance, multivariate analyses of covariance, correlations, linear regressions, multiple linear regressions, and power analyses.
Use multiple computer software packages to create spreadsheets and perform statistical routines.
Independently and proactively prepare mission-relevant proposal applications for toxicological, physiological, psychological, medical, and performance studies.
Develop technical reports, presentations, and publications.
Be willing and able to work nontraditional hours (e.g., nights, weekends) as needed.
Perform other duties as needed.
Ph.D. with 12+ years of experience in inhalation toxicology, or a related scientific field
A minimum of 15 years of experience proposing and conducting original research, including the design and implementation of protocols with animal models, data collection and analysis, and report production.
Extensive experience in toxicology studies utilizing small animals.
Strong background in toxicology research methodology with experience in research methods, design, and statistical analysis in a research setting.
Proficiency in Microsoft Outlook, Word, PowerPoint, and Excel.
Proficiency in the use of common statistical analysis software, to include SigmaPlot, SPSS and SAS.
Strong technical writing background with experience in writing research proposals, standard operating procedures, animal use protocols for approval by the Institutional Animal Care and Use Committee (human use/Institutional Review Board protocols a plus), technical reports, journal articles, and conference papers.
Excellent communication and interpersonal skills and ability to work cooperatively in a team environment.
Self-motivated and capable of working independently and with others.
Ability to obtain Secret Clearance
PhD plus 15 years of relevant experience
Experience in a military or medical research environment is highly desired
Demonstrated experience and success responding to research funding and grant requests for proposals.
The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.