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Job Details

Bristol Myers Squibb

Scientist - Discovery Protein Formulation

Science and Research



Princeton, New Jersey, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

Nonclinical Research and Development (NCRD) is an integrated function with responsibility for characterizing nonclinical safety and disposition characteristics of the entire BMS Research and Development pipeline programs, with critical role from early discovery to submission of marketing authorization applications. We utilize our deep expertise in toxicology/pathology, ADME, PK/PD, biopharmaceutics and Bioanalytics in all modalities (small and large molecules, cellular therapies and other novel modalities) to collaborate with peer R&D functions to identify and solve issues, discover high quality drug candidates, enable their clinical development and successful marketing authorizations across the globe.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Job Profile

In Discovery Pharmaceutics & Analytical Sciences (DPAS), you will have the ability to impact the lives of patients by working with multi-disciplinary research teams to help discover novel, efficacious and safe therapeutic molecules. BMS is looking for a motivated Scientist with a desire to contribute to the fast paced discovery matrix environment by conducting biophysical characterization and preformulation studies for potential new biologic candidates. The ideal candidate would have an understanding of biophysical properties of new biologic candidates as they relate to compound liability and developability profiles.

Job Responsibilities

  • Ability to carry out biophysical characterization and preformulation studies on potential new biologic candidates, with the purpose to define their developability and liability profiles.

  • Provide experimental and computational input to protein discovery scientists during design and screening of new biologics entities and enable drug design from lead optimization to the point of candidate identification, characterization and selection.

  • Assist in the design and development of formulations suitable for use in drug discovery pharmacology studies, PK studies and initial exploratory toxicology studies.

  • Participate in driving the strategic direction of the Discovery Pharmaceutics & Analytical Sciences group to further its ability to act as a problem solving entity for biologics discovery teams and provide seamless transfer of candidates to development.

  • Advance the abilities of the larger preclinical optimization organization to develop expertise in scientific areas which can enable our understanding of the role of biophysical properties in the overall biopharmaceutical performance of proteins, antibodies and other large molecules.

Basic Qualifications

  • Bachelor's Degree and 5+ years of academic / industry experience OR

  • Master's Degree and 3+ years of academic / industry experience OR

  • PhD and No experience required

Preferred Qualifications

  • PhD with 0-5 years or a B.S/M.S with 3-8 years of experience in industry in Pharmaceutical/ Protein/Analytical Chemistry, or academic equivalent highly preferred.

  • Knowledge of basic protein chemistry and biopharmaceutical principles as they apply to drug discovery and drug delivery of proteins, antibodies and other large molecules.

  • Understanding of biophysical properties and analytical methods used for characterization of proteins and other large molecules and how they relate to the biologics’ in vivo delivery and disposition.

  • Strong understanding of preformulation aspects for proteins, antibodies and other large molecules is necessary along with ability to guide the generation and interpretation of preformulation data as it relates to the overall discovery process.

  • Good written and verbal communication skills are a must.

  • Excellent interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required.

  • The ability to think innovatively and reduce such thinking to practical implementation is desired.

  • Knowledge on use of computers and databases for data collection, compilation, analysis and information dissemination is a must.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.