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Principal Scientist - siRNA Analytics

Science and Research



San Diego, California, United States

4 FDA approved drugs; 15+ clinical candidates; 400+ patents; 21 years of NIBR - San Diego history!<br>The Global Discovery Chemistry Analytical team is seeking a highly motivated Principal Scientist to help drive innovation in targeted siRNA delivery. As one of the local scientific leaders in siRNA, you will be working closely with a global team of experts to advance our therapeutics and to drive our understanding of selective delivery of siRNA. <br><br>Your responsibilities include, but are not limited to,<br>• Characterization of oligos and siRNA using appropriate analytical techniques<br>• Evaluate oligonucleotide PK and metabolism in cells, tissues, and biofluids, using standard oligonucleotide analytical methods (Stem-loop RT-qPCR, PNA fluorescence hybridization, or LC-MS)<br>• Design, develop, and troubleshoot SOPs for bioanalytical assays<br>• Identify and drive the identification of solutions to innovate the field of siRNA therapeutics <br>• Learning agility towards new concepts and ability to incorporate and exploit ideas across different teams<br>• Summarize and present results to team members <br>• Apply automation or collaborate with automation experts to improve efficiency<br><br><br>[#video#{#400,300#}#/video#]