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Research Scientist, In Vivo Pharmacology - CVM

Science and Research



Cambridge, Massachusetts, United States

Cardio-metabolic disease is the leading cause of death worldwide, taking an estimated 17.9 million lives each year. Obesity not only directly contributes to risk factors such as dyslipidemia and type 2 diabetes but also leads to the development of cardiovascular disease mortality independent of other risk factors. The Cardiovascular and Metabolic (CVM) Disease Area at the Novartis Institutes for Biomedical Research (NIBR) is dedicated to the creation and development of innovative and transformative medicines to prevent and treat cardio-metabolic disease. <br><br>We are seeking a highly motivated scientist to join our in vivo pharmacology group to help discover new therapies for cardio-metabolic disease. In this role, you will be responsible for planning, executing, and analyzing in vivo pharmacology experiments in preclinical models of metabolic disease. You will be working in a highly matrixed, team-oriented, and collaborative environment. <br><br>The successful candidate is expected to perform and excel in the following areas: <br>• Assist in the design, development, characterization, implementation and validation of relevant preclinical models for identifying and profiling of metabolic targets<br>• Plan and perform in vivo pharmacology studies to evaluate metabolic treatment strategies including efficacy, PK/PD and mechanism of action analyses. <br>• Perform biochemical and/or histological analyses of samples<br>• Document, analyze and interpret experiments in a timely manner. <br>• Present results in lab and department meetings<br><br>The pay range for this position at commencement of employment is expected to be between $80,000.00 and $100,000.00 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. <br><br>[#video#{#400,300#}#/video#]