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Job Details

Bristol Myers Squibb

Principal Scientist, Translational Bioinformatics Late Stage Immunology, Cardiovascular, Fibrosis and Neurology

Science and Research



Cambridge, Massachusetts, United States

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

We are seeking a highly motivated bioinformatician with preclinical or clinical experience to join our Translational Bioinformatics late stage Immunology, Cardiovascular, Fibrosis, and Neurology (ICFN) team, within Informatics and Predictive Sciences group. The successful candidate will help advance Bristol-Myers Squibb’s industry leading ICFN programs through the strategic application of cutting edge bioinformatics approaches.


Analyze various -omic-scale data generated from human subjects in BMS clinical trials and multi-modal Real-World Datasets (RWD) from commercial partners, pre-competitive consortium, and public resources. These rich data resources include clinical and demographic data, RNA-Seq, high throughput proteomics, Exome and Whole Genome Sequencing, and multiplex flow cytometry. Perform deep and innovative analyses of these data to build comprehensive understanding of disease mechanisms and patient heterogeneity, identify non-responders to standards of care with unmet medical needs, generate testable hypotheses for drug combination strategies, and inform new target selection and prioritization.

Optimize reverse translation through application of late-stage clinical data sets to inform early clinical trials and the discovery pipeline, in close collaboration with teams across Research and Early Development, including bioinformaticians, statisticians, biologists, biomarker leads, and clinicians. Define and execute statistical/computational analysis plans.

Participate in authorship of scientific reports and present methods and conclusions to publishable standards.

Basic Qualifications:

  • Bachelor's Degree in bioinformatics, engineering, statistics, physics, molecular biology, genetics, or a similar discipline and 8+ years of academic / industry experience
  • OR Master's Degree in bioinformatics, engineering, statistics, physics, molecular biology, genetics, or a similar discipline and 6+ years of academic / industry experience
  • OR PhD in bioinformatics, engineering, statistics, physics, molecular biology, genetics, or a similar discipline and 4+ years of academic / industry experience

Preferred Qualifications:

  • Ph.D. in bioinformatics, engineering, statistics, physics, molecular biology, genetics, or a similar discipline.
  • Five (5) or more years relevant experience in preclinical or clinical research.
  • Proven track record of independent research under minimal supervision.
  • Experience designing complex experiments and statistical analysis plans.
  • Strong background in -omic (DNA, RNA, epigenetic, proteomic) data analysis and biological interpretation.
  • Working knowledge of commercial and publicly available biological databases including NCBI, Ensembl, ArrayExpress/GEO and SRA is expected.
  • Solid background in Immunoscience, fibrosis, cardiovascular or neurological diseases.
  • Strong problem-solving and collaboration skills, rigorous and creative thinking
  • Ability to communicate effectively with biologists, clinicians, biostatisticians and computational scientists.
  • Proficiency using R and Bioconductor packages is required.

The starting compensation for this job is a range from $121,000-$167,200, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and the where the job is performed.

Final individual compensation will be decided based on demonstrated experience.

For more on benefits, please visit our

Eligibility for specific benefits listed on our BMS Careers site may vary based on the job and location.


If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

COVID-19 Information
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.