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Principal Scientist, Fibrosis Research

Science and Research



Cambridge, Massachusetts, United States

45%- this is the number of deaths attributable to fibrotic disorders worldwide across all organs and are the result of dysregulation of the extracelluar matrix in response to acute and chronic injury. We are building a dedicated research group within Disease Area X focused on delineating the key factors/pathways involved in fibrotic diseases and developing transformative new therapies for patients. The successful candidate will join a team working to discover and progress the next wave of new therapeutics that will halt fibrotic diseases across multiple organs.<br><br>We seek candidates who have backgrounds in progressing drug discovery projects from target concept and validation, to discovery and optimization of novel therapeutic modalities, and delivering drug candidates for pre-clinical studies. A track record of hands-on mentorship and development of other scientists is essential to success in the role. Other key skills include a proven ability to formulate and implement project strategy in collaboration with stakeholders, to lead decision-making for project teams, to design and plan experiments in collaboration with bench scientists, and to build effective teams directed towards solving complex scientific problems.<br><br>The successful candidate will lead and mentor multiple scientists, work collaboratively across DAx, other NIBR Disease areas and Functional areas, establish external partnerships (academic and biotech), and interact with a global network of researchers working towards the understanding and discovery of novel therapeutics that address fibrosis across multiple organs.<br><br>Key responsibilities:<br><br>* Formulate novel approaches to targeting fibrosis across multiple organ types<br>* Lead multi-disciplinary project team to decision milestones<br>* Line management responsibility for several research scientists