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Principal Scientist, Biomarker Dev Molecular Soluble Cellular Sciences

Science and Research

Scientist

No

Cambridge, Massachusetts, United States

Multiple positions available:<br><br>1 purpose...to reimagine medicine and strive to be one of the leading companies in Precision Medicine through the delivery and execution of an end-to-end biomarker strategy! We deliver “fit for purpose” integrated biomarker in our clinical trial leveraging diverse expertise and knowledge in genetics, genomics, protein and cellular biology, digital devices, and state of the art data sciences. Our innovative spirit enables the development and application of cutting-edge technologies that address key clinical questions across programs in many disease areas. <br><br>What you’ll be doing<br>As a Principal Scientist within Biomarker Development Molecular & Cellular Sciences group you will partner with disease area, medical experts to define and execute robust “fit for purpose” clinical biomarker strategy that address key scientific and clinical questions for programs in early and late clinical development phases.<br>Your responsibilities will include, but not limited to:<br>• As biomarker clinical expert in project teams, you will provide scientific and technical insights, contribute to the overall clinical study biomarker strategy and plan, lead the execution and support interpretation of biomarker data to enable proof of mechanism, proof of biology, safety and efficacy understanding and patient selection.<br>• As biomarker study lead in clinical studies (early and late phases), you will be accountable for the definition and execution of the cellular and soluble biomarker plan and the successful implementation of internal and external “fit for purpose” biomarker assays.<br>• Manage activities and supervise laboratory in compliance with Novartis guidelines and Good Clinical Practice.<br>• Identify and evaluate new innovative biomarker technologies to cover biomarker needs and gaps in early and late projects.<br>• Partner with outsourcing functions to evaluate new CROs, drive transitioning and monitoring of internally developed assays to external vendors.<br><br>The pay range for this position at commencement of employment is expected to be between $112,800 and $186,00/year; however, while salary ranges are effective from 1/1/23 through 12/31/23, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.<br><br>This position will be located at Cambridge, MA site and will not have the ability to be located remotely. <br><br><br>[#video#https://www.youtubeno-cookie.com/embed/ggbnzRY9z8w{#400,300#}#/video#]