Principal Scientist - Separation and Analysis Technology Team Lead

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Responsibilities:

This individual will be responsible for leading a small team providing separation science support for the drug discovery/medicinal chemistry group at BMS in San Diego, CA. He or she will lead a team of 1-2 BMS scientists and a varying number of external service providers, to deliver non-GLP separation science support for the site, including

• A high throughput small molecule purification service, using both preparative liquid chromatography (HPLC) and preparative supercritical fluid chromatography (SFC), for achiral and chiral separations, including needed method development, and post purification processing.
• Local onsite support for separation and physical property measurements, and coordination with team members at other sites to deliver capabilities not available locally.
• Ensuring operational support of a fleet of analytical LCMS instruments used by medicinal chemists for routine reaction checking and compound QC; ensuring that the infrastructure is fully operational, tracking usage and output metrics, interacting with medicinal chemists, and troubleshooting problems as they arise.
• Alignment with the external service provider to ensure that scheduling and training are matched to requirements to ensure smooth and efficient operation of the lab.

In addition to the operational role described above, the individual will be responsible for working with management to develop, implement, and update the strategic plan for separation science at the expanding site, including:

• Participating in design and eventual move into a newly constructed purpose-built facility adjacent to the existing site in San Diego.
• Identifying and completing continuous improvement projects that may include chromatography method development, infrastructure improvements, IT and process improvements, quality improvements, etc.

The individual’s immediate supervisor in this role will be located at a different site (in New Jersey). Frequent telecommunication and occasional (1-2 times/year) travel will be required between sites.

Basic Qualifications:

• Bachelor’s Degree & 8+ years of relevant academic and / or industry experience

Or

• Master’s Degree & 6+ years of relevant academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences & 4+ of relevant academic and / or industry experience

Preferred Qualifications:

• Ph.D and 4+ years of relevant industry experience
• Extensive experience in analysis and purification of small molecules and/or peptides by reverse phase HPLC and SFC, and in mass spectrometry.
• Demonstrated strategic leadership skills.
• Demonstrated problem-solving skills, including troubleshooting processes, instruments, and data management issues.
• Ability to work independently, without local supervision.
• Strong written and oral communication skills.
• Proven record of accomplishment of successful project management and completion in a highly matrixed environment.
• Experience in a high throughput environment managing large numbers of samples and associated data is strongly desired.
• Experience in a drug discovery environment is strongly desired.
• Experience in computer programming (one or more common or instrument-specific languages), laboratory automation, and/or process optimization are highly desired.
• Supervisory experience is desirable.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.