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Merck Senior Scientist, Oral Formulation Sciences in Rahway, New Jersey

Job Description

Our company's Pharmaceutical Sciences organization translates molecules to medicines, working from the discovery interface through registration stability manufacturing by designing, developing and scaling-up the formulation, device, and manufacturing process. Driving drug product design from the bench top to the Good Manufacturing Practice (GMP) manufacturing facilities, our Scientists use cutting edge science to transform drug delivery and manufacturing technology to positively impact patients.

The successful candidate will be a passionate Scientist with strong academic fundamentals and a drive to develop new medicines to improve human health. In this role, the individual will be responsible for supporting the formulation development of new chemical entities as part of a matrix team from initial first in human formulations (suspensions, solutions, capsules, tablets) through final market formulation definition and manufacturing process robustness assessment.

Primary Responsibilities:

  • Propose new, innovative approaches for product development, generate experimental designs, execute experimental plans and interpret data.

  • Support internal capability development by evaluating new technologies and deploying them to pipeline assets.

  • Collaborate effectively within and across functional areas and possess advanced knowledge or experience in a specialized scientific area. The desired individual is someone who will bring knowledge and creativity to the position as well as have the discipline to drive results.

  • Execute formulation and process development activities using Design of Experiments (DOEs) for new chemical entities or life cycle management opportunities.

  • Coordinate development activities with process chemistry, preformulation, analytical, and physical characterization groups.

  • Outsource/coordinate formulation development or clinical manufacturing at Clinical Research Organization (CROs)/Contract Manufacturing Operation (CMOs).

  • Facilitate manufacturing, packaging and release of clinical supplies for clinical studies, assist in scale up activities at pilot and commercial scale, and summarize results in technical reports and presentations.

  • Enhance our professional image and competitive advantage through patents, presentations, publications and professional activities and advance areas such as science and technology development, technical and business strategic improvements, business process innovations.

  • Maintain awareness of relevant new and current technologies, capabilities, and effectively share this knowledge with others.

Education Minimum Requirements:

  • Ph.D. in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline. Bachelor of Science (B.S.) or Master of Science (M.S.) degree in Engineering, Pharmaceutical Sciences or related discipline with minimum of 6 years' relevant industrial experience.

Required Experience and Skills:

  • Proven ability to identify and develop innovative ideas.

  • Demonstrated ability to independently design and execute complex experiments and data analysis.

  • Ability to work effectively with team-members of diverse skill sets and backgrounds.

  • Strong verbal and written communication skills.

Preferred Experience and Skills:

  • Pharmaceutical development experience.

  • Demonstrated ability to identify, fundamentally characterize and address manufacturing challenges through the development and optimization of novel production technologies.

  • Experience with advanced drug product manufacturing technologies, including: continuous manufacturing, Three Dimensional (3D) printing, controlled release and/or oral delivery of large molecules.

  • Experience with process modeling, simulation and automation integration in the pharmaceutical and/or industrial manufacturing sector.

  • Desire to build new capabilities through the evaluation of new technologies and hands-on optimization of existing technologies.

  • Demonstrated ability to apply the principles of physical/organic chemistry, physical pharmacy and materials science to solving practical pharmaceutical development problems.

  • Hands-on experience in pharmaceutical pilot plants.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Merck & Co., Inc., Kenilworth, New Jersey, USA is known as “Merck” in the United States, Canada & Puerto Rico. We are known as “MSD” in Europe, Middle East, Africa, Latin America & Asia Pacific. We are a global biopharmaceutical leader with a diverse portfolio of prescription medicines, oncology, vaccines and animal health products.

We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to Inspire our employees as we learn, develop and grow in our careers. We are proud of our 125 years of service to humanity and continue to be one of the world’s biggest investors in Research & Development.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.





In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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We are an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Search Firm Representatives Please Read Carefully

Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:




VISA Sponsorship:


Travel Requirements:


Flexible Work Arrangements:


Valid Driving License:

Hazardous Material(s):

Active Pharmaceutical Ingredients

Number of Openings:


Requisition ID: R39298