Thermo Fisher Scientific Bioinformatics Scientist - Primer Design in South San Francisco, California

Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

Location/Division Specific Information

South San Francisco, CA.

The candidate will be part of the Bioinformatics R&D team in Clinical Next Generation Sequencing Group and will be responsible for primer design for the development of targeted sequencing panels, pipelines and algorithms for next-generation DNA sequencing.

How will you make an impact?

As the leading supplier of life science technology and related applications, we are helping life scientists understand and use the power of genomics to pursue new scientific discoveries and advance clinical research in personalized medicine.

What will you do?

  • Design assays for custom targeted sequencing panels for external and internal researchers

  • Understand the core scientific questions and design assays to best address these questions.

  • Develop, maintain, and operate bioinformatics pipelines for assay design, data mining and analysis

  • Improve the designs by iterative analysis of the sequencing data obtained. Develop heuristic rules, optimization, and algorithms to improve the design pipeline.

  • Analyze sequence data and mine public databases for sequence content.

  • Collaborate closely with the molecular biologists, product management, sales, experimental researchers and other members of the Bioinformatics team

  • Work closely with external customers to understand and provide the best design solution that meets their needs

How will you get here?


  • This position requires the knowledge and skills normally acquired through completion of a MS/PhD in Bioinformatics, Computational Biology, Computer Science, Genomics or related field. Three or more years of relevant working experience is required.

  • Experience working and developing bioinformatics production systems.

  • The candidate must have experience in Perl / Python programming, shell scripting and SQL.

  • The following are also required: hands-on experience with the relevant sequence analysis tools (e.g. Blast, Clustalw, bowtie, etc.)

  • An excellent understanding of genomic databases and their annotations (GenBank, RefSeq, ENSEMBL, dbSNP, UCSC genome browser); a good understanding of the biology behind genotyping, gene expression profiling, comparative genomics and genetic mapping; an appreciation of the use of statistical methods and mathematical models in the interpretation of biological data; experience with next generation sequencing data

  • Preferred assay design experience.

Knowledge, Skills, Abilities:

  • Strong communication and organization skills are needed.

  • Position level commensurate on experience.

At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

Apply today!

If you are an individual with a disability who requires reasonable accommodation to complete any part of our application process, click here at for further assistance.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.