Thermo Fisher Scientific Process Development Scientist 2 (Purification) in St. Louis, Missouri

Job Description

Process Development Scientist 2 (Purification)

When you join us at Thermo Fisher Scientific, you’ll be part of a smart, driven team that shares your passion for exploration and discovery. With revenues of $22 billion and the largest investment in R&D in the industry, we give our people the resources and opportunities to make significant contributions to the world.

Location/Division Specific Information

St. Louis, MO

How will you make an impact?

Provide moderately complex analyses in a biology environment within defined procedures and practices. Participate in development of scalable processes with improved product yield and reduced costs in a biologics environment. Support internal development and/or manufacturing operations. May research and implement new methods and technologies to enhance operations. Make detailed observations and reviews, documents, and communicates test results; recommends solutions. Maintain lab equipment.

What will you do?

  • Develop recombinant protein purification processes, including chromatography process, ultrafiltration / diafiltration, nanofiltration, process characterization and optimization, process scale up, scale down model qualification, viral clearance validation.

  • Assist with development of transfer of purification processes which can be scaled up for protein production and facilitates the Technology Transfer to Downstream Manufacturing group.

  • Assist with the design of experimental plans based on the defined deliverables.

  • Conduct semi-routine and moderately complex tasks and sample analyses to support process development. Work with Process Development and Manufacture groups to trouble-shoot process challenges.

  • May function as a process subject matter expert in a cGMP environment.

  • Record results in notebook accurately, clearly, and regularly.

  • Assist with preparing protocols, reports, and test methods.

  • Maintain and ensure safe laboratory environment and work practices.

  • Help to maintain laboratory and order common supplies.

  • Execute, record, and evaluate experimental data appropriately, including the writing and revising of process development reports and technology transfer protocols as needed.

How will you get here?

Education:

Bachelor's degree or Master’s degree in biology, chemistry, biochemistry, chemical engineering, or a related field.

Experience:

  • With Bachelor’s degree, minimum of 2 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory. Relevant industry experience preferred.

  • With Master's degree, no experience required; related industry experience preferred.

  • Experience using advanced statistical software packages and experience with design of experiments (DoE) software (i.e. MiniTab, JMP) preferred.

Equivalency :

Equivalent combinations of education, training, and relevant work experience may be considered.

Knowledge, Skills, Abilities

  • Applied knowledge from the experience of applying the principles, concepts, and practices of discipline.

  • Working knowledge of GMP/GLP regulations in cGMP/cGLP manufacturing environment preferred.

  • Solid lab skills.

  • Good problem solving and critical thinking skills.

  • Good writing, communication and presentation skills.

  • Good MS Excel, PowerPoint and Word skills.

  • Excellent organization and planning skills.

  • Strong attention to detail and ability to adhere to standards procedures.

  • Ability to design and execute tasks and studies based on the deliverables.

  • Ability to analyze and summarize moderately complex scientific data.

  • Ability to properly document work and write reports.

  • Ability to function in a rapidly changing environment.

  • Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.

  • Ability to make decisions that require choosing between limited alternatives to resolve problems of moderate complexity.

At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

If you are an individual with a disability who requires reasonable accommodation to complete any part of our application process, click here at https://jobs.thermofisher.com/page/show/eeo-affirmative-action-statement#accessibility for further assistance.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.