Executive Director, Head of Protein Homeostasis

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

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Position: Head of Protein Homeostasis

Location: Brisbane or San Diego (Brisbane preferred)

Position Summary

The leader of Protein Homeostasis (PH) will be responsible for developing and implementing the vision and strategy for the PH Center of Excellence. They will partner with leadership in Small Molecule Drug Discovery and the Thematic Research Centers to drive PH programs towards the invention of new medicines. The leader will coordinate biochemistry, biophysical, cellular and molecular pharmacology, chemistry, proteomics, and structural biology activities necessary to drive the PH platform. The leader will inspire and develop talent to maintain a highly engaged and productive team.

Key Responsibilities

• Lead Protein Homeostasis Center of Excellence, which includes cross-functional teams dedicated to protein expression, structure elucidation, proteomics, chemistry, biophysics/biochemistry, and molecular/cell biology

• Influence and guide PH science to identify novel targets across disease areas including Oncology, Hematology, Immunology, Cardiovascular, Neuroscience, & Fibrosis

• Prioritize and leverage approaches to PH including CELMoDs, heterobifunctional degraders, intrinsic degraders, and emerging technologies for proximity-induced pharmacology

• Actively allocate and manage internal/external resources

• Conceptualize and define the PH future state vision with emphasis on novel pharmacological entry points, driving drug discovery and platform technology development

• Partner with leaders across our biology and functional network to identify and deliver therapeutic advances

• Collaborate across Small Molecule Drug Discovery to identify novel ligands through strategic screening approaches

• Engage at relevant governance forums

• Actively participate in evaluating PH relevant assets, technologies, and collaborations

• Lead team’s efforts in key academic and industry alliances

• Develop next generation of leaders utilizing intentional recruiting, retention, and career development strategies

Basic Qualifications

Master's Degree

20+ years of academic / industry experience

or

PhD15+ years of academic / industry experience

10+ years of leadership experience

Qualifications & Experience

• Ph.D. in Cellular/Molecular Pharmacology, Chemical Biology, Chemistry, Structural Biology, or related field

• >12 years of relevant experience in chemical biology and/or protein homeostasis

• >5 years leading scientific efforts in targeted protein degradation induced by monovalent or bivalent ligands

• Proven track record of delivering quality scientific innovation translating to the invention of development candidates

• Experience leading through others

• Demonstrated ability to recruit, retain, and develop talent

• Proficient collaborative skills across drug discovery functions

• Significant insights related to chemical biology approaches preferred

The starting compensation for this job is a range from $241,434 – 301,792, plus incentive cash and stock opportunities (based on eligibility).

The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.

For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

COVID-19 Information
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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