Biopharmaceutics Post-Doctoral Research Fellow

Job Description

Be a part of the legacy: Postdoctoral Research Fellow Program

Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

We are seeking a Postdoctoral Fellow that is passionate about advancing the predictive capability of in vitro drug dissolution models to join the Biopharmaceutics group part of the Sterile and Specialty Products at our company Research Laboratories in Rahway, New Jersey. The successful postdoctoral fellow will use conventional and next-gen in vivo predictive dissolution apparatus to establish the new in vivo predictive dissolution foundation and to fine-tune for the improvement of IVIVC and the in vivo prediction from this in vitro study combined with in silico modeling. The postdoctoral fellow will work in close collaboration with pharmaceutical scientists, bioengineers, analytical scientists, and formulation scientists at our company. This fellowship intends to focus on developing the candidates scientific and professional development and is intended to last for 3 years.

Responsibilities include but are not limited to:

• Conduct research under mentorship of the Biopharmaceutics team and Analytical science team (SMARD: small molecule analytical research & development) involving in vitro dissolution, IVIVC (connecting plasma profile from pre-clinical and clinical studies), connecting in vitro dissolution to in vitro permeation study (Gut-on-a-chip), and in silico modeling based on the in vivo predictive dissolution profiles.

• Willingness to troubleshoot and problem solve complex transport phenomena in dissolution settings and modeling.

• Collaboration with our company's colleagues in Oral Formulation Sciences, Discovery Pharmaceutical Sciences, AR&D Sciences, Exploratory Science Center, and our company's 3D Technologies.

• Active participation in department and group meetings, and postdoctoral program trainings and meetings.

• Continued development of your science communication skills through literature reviews, manuscript authoring, internal and external conference attendance.

Education Minimum Requirement:

• PhD in Pharmaceutical Sciences, Biopharmaceutics, Pharmacokinetics, Analytical Sciences, Physiology, Pharmacology, Bioengineering, Chemical Engineering, Drug Delivery, or related field.

• Less than 3 years of postdoctoral experience or plans to graduate with a PhD or will you have completed your PhD within the next year

Required Experience and Skills:

• Experience in analytical methodologies (e.g. HPLC and LC-MS)

• Experience in oral absorption and gastrointestinal biology

• Ability to work both independently and collaboratively

• Strong written and oral communication skills

Preferred Experience and Skills:

• Experience in in silico modeling software (e.g. SimCyp and GastroPlus)

• Experience/interests in in-vitro dissolution (compendial dissolution apparatus) for drug absorption studies or assessing drug delivery systems

• Experience in transport analysis (mathematical model)

• Willingness to expand your expertise and to be a champion in the new field

• Familiarity with in vitro dissolution apparatus

• Knowledge of intestinal biology, oral absorption, and pharmacokinetics

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

MRLpostdoc

Who we are …

We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Post Doc:

Under New York City, Washington State and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected salary range:

$75,000.00-$86,000.00

Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here.

For positions located in the United States and Puerto Rico – Subject to applicable law, all new hires (including internal transfers) must demonstrate that they are fully vaccinated against COVID-19 or that they qualify for a medical or religious exemption to this vaccination requirement. New hires (including internal transfers) to a position that, as determined by the Company, requires routine collaboration with external stakeholders (such as roles in health services or customer-facing commercial or research-based roles) (“Customer-Facing Role”) who are not vaccinated must qualify for a medical or religious exemption and be in a position that the Company determines can accommodate unvaccinated employees without causing an undue burden to business operations. If, following dialog with the candidate as appropriate, it is determined that the candidate either a) does not qualify for a religious or medical exemption or, b) for candidates applying for Customer-Facing roles, it is determined that allowing the candidate to work without vaccination would cause an undue burden to the Company, the candidate will be ineligible for hire or transfer, or any offer of employment or transfer (if applicable) will be revoked. Please note that notwithstanding the approval of any reasonable accommodation, the Company reserves the right to monitor, modify, or revoke any such accommodation if it is determined, following dialog with the employee, that the accommodation is no longer effective or results in an undue burden to the Company.

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Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Shift:

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Number of Openings:

Requisition ID:R215852