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Job Details


Merck & Co, Inc

Associate Principal Scientist, Genomic Data Science

Science and Research

Scientist

No

Boston, Massachusetts, United States

Job Description

The Genome and Biomarker Sciences (GBS) team is seeking a passionate and creative data scientist to drive the integration and utilization of wide-ranging multi-omics molecular profiling and functional genomics datasets at the single-cell and tissue scales to enable the discovery of the next wave of therapeutics. Discovery research at our company is driven by a deep interest in the underlying biology of human disease, and how diverse points of intervention can be modulated to extend life and improve quality of life. You will collaborate closely with colleagues across the Discovery Research enterprise, including computational biologists and software development professionals to design intelligent and extensible analytic solutions for therapeutic target discovery, and will be based at our Research Laboratories in Cambridge, MA.

In this exciting role, you will:

  • Collaborate with teams across therapeutic areas to identify data sets for integration and interrogation, to aid in the discovery of novel therapeutic targets.

  • Work with bioinformatics and data science teams to build scalable data models, analytic frameworks and visualizations for diverse biological data.

  • Engage with Discovery Teams to apply machine learning and statistical methods for the analysis and mining of multi-omics (genomics, transcriptomics, proteomics, etc.) datasets at scale.

  • Work with in-house, open-source and/or commercially available software platforms for the processing and integrative analysis of multiple -omics data types

Education Minimum Requirement:

  • Ph.D. in Computational Biology, Biostatistics, Statistics, Mathematics, Computer Science, Molecular Biology, or a related field, +4 years experience, or M.S. or equivalent and 10+ years relevant data science experience.

Required Experience and Skills:

  • Experience with data transformation, integration, mining and analyses to generate new testable hypotheses.

  • Familiarity with public databases and repositories of DNA and RNA profiling data

  • Demonstrated experience in the computational analysis and interpretation of large-scale molecular profiling datasets

  • Proficiency in statistical programming languages, such as R or Python

  • Familiarity with scalable database architectures to enable efficient integration of diverse biologic datasets at scale

  • Excellent attention to detail and strong communication (oral and written) skills

  • Highly self-motivated and capable of prioritizing deliverables among multiple simultaneous projects

  • Experience building strong relationships within highly collaborative, multidisciplinary teams

  • Experience with high-performance Linux cluster and cloud computing

Preferred Experience and Skills:

  • Proficiency in machine learning and statistical inference methodologies

  • Strong publication record

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.

GBx

DATA2020

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Number of Openings:

1

Requisition ID:R124389