Senior Scientist, Process Analytical Technology

Job Description

In April 2020, our Company announced plans to consolidate our New Jersey campuses into a single New Jersey headquarters location in Rahway, NJ by 2023. Therefore, this role will be temporarily based in a and exact timing of the departmental move to Rahway, NJ will be communicated at a future date.

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

Our company seeks a talented scientist to join our Process Analytical Technology (PAT) development team, part of the global Analytical Chemistry in Development and Supply (ACDS) organization. We currently have an exceptional career opportunity for a Senior Scientist at the Rahway, NJ site. On-site and/or hybrid work.

As a member of the ACDS – PAT team, this person will integrate a motivated and inclusive team of expert scientists passionate PAT tools application from process development to routine manufacturing. The PAT Senior Scientist will develop, implement, and introduce new in-line, on-line and at-line analytical technology to support API processes. Have a strong technical background in spectroscopy (Raman, FTIR, NIR), multivariate (chemometrics) modelling skills and process control for pharmaceutical API processing and hands-on-experience and in-depth understanding of PAT concepts and its application to pharmaceutical development.

Key responsibilities:

• Develop and validate in-line, on-line or at-line PAT methods to monitor and control process parameters and/or product quality attributes.
• Coordinate and participate in cross-functional projects.
• Support PAT scale-up and technology transfer to large scale manufacturing.
• Write technical protocols and reports ensuring compliance with applicable regulatory guidelines.
• Support scientific documentation, validation of PAT methods and contribute to regulatory filings.
• Operate lab and pilot scale PATs
• Apply chemometrics and multivariate data analysis techniques for PAT calibration and spectral data interpretation in alignment with process data

Required Qualifications:

• Ph.D. or M.S. degree in Chemical Engineering, Analytical Chemistry or related discipline. (Exceptions may be considered where relevant experience may exist.)

Experience and Skills:

• Ph.D. + 0 years OR M.S. +3 years of industry experience.
• Excellent organizational and communication skills.
• Must be able to work effectively in a multi-functional team environment
• Fundamental understanding of vibrational spectroscopy. pectral interpretation & analysis.
• Demonstrated capability in development of Process Analytical Technologies.
• Good knowledge of qualitative and quantitative chemometric model building.
• Ability to work independently in a multidisciplinary and team environment.
• Fast learner, self-motivated to drive innovation with a problem-solving mindset.

Preferred Experience and Skills:

• Proficiency in PAT development & validation using chemometric techniques.
• Hands-on expertise with NIR, FTIR and Raman, on-line HPLC, on-line Mass spectrometry.
• Hands-on expertise using multivariate software platforms such MATLAB, SIMCA, Unscrambler for data analysis.
• Expertise with PAT Manufacturing systems automation (SIPAT, Modbus, OPC, PLC).

Our Manufacturing & Supply Division is dedicated to being the most trusted supplier of bio-pharmaceuticals worldwide. Our facilities, along with our external contractors, suppliers, and partners, create a reliable global manufacturing network that’s devoted to delivering a high quality, reliable supply to customers and patients on time, every time.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

New hires in office-based roles in the US & Puerto Rico will be required, subject to applicable law, to demonstrate that they have been fully vaccinated for COVID-19 or qualify for a medical or religious exemption to this vaccination requirement that can be accommodated without an undue burden to the operation. However, subject to applicable law, employees working in roles that the Company determines require routine collaboration with external stakeholders, such as employees in health services, customer facing commercial, or research based roles, will be required to be fully vaccinated as a condition of employment.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

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Flexible Work Arrangements:

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Requisition ID:R184173